четверг, 1 октября 2009 г.

Mylan wins FDA approval for generic Parkinson's drug

Oct 05, 2009 (Datamonitor via COMTEX) Mylan has announced that its subsidiary Mylan Pharmaceuticals has received approval from the FDA for its abbreviated new drug application, or ANDA, for Carbidopa and Levodopa tablets USP, 10mg/100mg, 25mg/100mg and 25mg/250mg.
Carbidopa and Levodopa tablets are the generic version of Bristol Myers Squibb's Parkinson's treatment Sinemet, 10mg/100mg, 25mg/100mg and 25mg/250mg. Mylan has launched this product.
Mylan and its subsidiaries comprise a global pharmaceutical company that develops, licenses, manufactures, markets and distributes generic, brand and branded generic pharmaceutical products and active pharmaceutical ingredients.

четверг, 24 сентября 2009 г.

buy Isosorbide Mononitrate

 Isosorbide mononitrate is in the class of drugs called nitrates that are used for treating and preventing angina. Other nitrates include nitroglycerin (Nitrostat, NitroQuick, Nitrolingual, Nitro-Dur and others) and isosorbide dinitrate (Isordil Titradose, Dilatrate-SR, Isochron). Nitrates are vasodilators (dilators of blood vessels). Blood returning from the body in the veins must be pumped by the heart through the lungs and into the body's arteries against the high pressure in the arteries. In order to accomplish this work, the heart's muscle must produce and use energy ("fuel") which requires oxygen brought to the heart by the blood.

Angina pectoris (angina) or "heart pain" is due to an inadequate flow of blood (and oxygen) to the muscle of the heart. Nitrates, including isosorbide mononitrate, correct the imbalance between the flow of blood and oxygen to the heart and the work that the heart must do by dilating the arteries and veins in the body. Dilation of the veins reduces the amount of blood that returns to the heart that must be pumped. Dilation of the arteries lowers the pressure in the arteries against which the heart must pump. As a consequence of both effects, the heart works less and requires less blood and oxygen.


Buy Iressa Online. Buy Cheap Iressa



 Iressa (generic name: Gefitinib) is a drug used to treat non-small cell lung cancer, which is one type of lung cancer.

Iressa is a selective inhibitor of a growth factor that is found in non-small cell lung cancer. By blocking the action of the growth factor Iressa may slow or stop the growth of non-small cell lung cancer.

Iressa is currently only indicated for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in patients who have previously received chemotherapy.
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buy Insulin Glargine (Lantus)


What is Insulin Glargine injection?

INSULIN GLARGINE (Lantus®) is a human-made form of insulin. Insulin is a hormone produced naturally by the pancreas. Insulin lowers the amount of sugar in your blood. Keeping your blood sugar close to normal prevents or reduces long-term complications of diabetes including damage to the blood vessels, eyes, kidneys, or nerves. Insulin glargine is a long-acting insulin that is usually given once a day. The time-course of action of insulin may vary in different people and at different times in the same person. The time-course of action of insulin may also vary depending on the place where the insulin is injected, your body temperature, and your physical activity. A prescription is needed to buy insulin glargine. A prescription to obtain insulin syringes may or may not be required in the state where you live.

There are different types of insulin available. Each type has a different onset of action and a different duration of action in the body. You should learn which types you take and how you should administer them, and how each type acts in your body. Insulin glargine is labeled with its name, Lantus®. Insulin is obtained from beef, pork, or human sources.Beef insulin is no longer made in the US because of concerns of cow tissues spreading certain infections.

Do not change the type of insulin you are taking without talking to your prescriber. If you must switch the type of insulin you use, you should realize that you may need to monitor your blood sugar more frequently and that dosage adjustments may be needed before you are stabilized on the new type. Take care to learn and recognize the symptoms of hypoglycemia (low blood sugar) and know how you should treat these reactions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
• adrenal or pituitary gland problems
• diarrhea
• fever or infection
• injury or trauma
• kidney disease
• liver disease
• nausea, vomiting
• recent surgery
• thyroid disease
• pregnant or trying to get pregnant
• breast-feeding
• an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives

How should this medicine be used?

Insulin is for injection under the skin. Use exactly as directed. Do not use more insulin than prescribed. Do not use more or less often than prescribed. It is important to follow the directions given to you by your health care professional or prescriber. You will be taught how to inject insulin. If you utilize an insulin injector device, you will be taught how to use it, prime it, and how to refill the device with the insulin cartridges.

You will be taught how to administer doses before meals. You will also be taught how to adjust doses for activities and illness.

Always check the appearance of your insulin before using it. Insulin glargine should be clear and colorless like water. Do not use insulin glargine if it is cloudy, thickened, colored, or has solid particles in it.

Do not mix insulin glargine with any other insulin or diluent.

What drug(s) may interact with Insulin Glargine?

• other medicines for diabetes

Many medications may cause changes (increase or decrease) in blood sugar, these include:
• alcohol containing beverages
• angiotensin converting enzyme inhibitors (ACE inhibitors), often used for high blood pressure or heart problems (examples include captopril, enalapril, lisinopril)
• antiretroviral protease inhibitors (examples include indinavir, ritonavir, saquinavir)
• aspirin and aspirin-like drugs
• beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
• certain medicines used for mental depression, emotional, or psychotic disturbances
• chromium
• cisapride
• clonidine
• cyclosporine
• danazol
• diazoxide
• disopyramide
• epinephrine
• female hormones, such as estrogens, progestins, or contraceptive pills
• fenofibrate
• gemfibrozil
• glucagon
• growth hormone (somatropin)
• guanethidine
• isoniazid
• lithium
• metoclopramide
• male hormones or anabolic steroids
• medications to suppress appetite or for weight loss
• medicines for allergies, asthma, cold, or cough
• niacin
• nicotine (including nicotine found in patches and gum)
• pentamidine
• pentoxifylline
• phenytoin
• propoxyphene
• quinolone antibiotics, medicines used for infections (examples include ciprofloxacin, levofloxacin, norfloxacin)
• some herbal dietary supplements
• steroid medicines such as prednisone or cortisone
• sulfonamides, medicines for infection ( examples include Azulfidine®, Bactrim®, Gantrisin® Septra®)
• tacrolimus
• thyroid hormones
• water pills (diuretics)

Some medications can hide the warning symptoms of low blood sugar (hypoglycemia). You may need to monitor your blood sugar more closely if you are taking one of these medications. These include:
• beta-blockers, often used for high blood pressure or heart problems (examples include atenolol, metoprolol, propranolol)
• clonidine
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buy Indomethacin online



Indometacin (brand names include: Indocin / Indocid / Inmecin / Indochron E-R / Indocin-SR / Flexin Continus / Indolar / Indomax / Indomod / Pardelprin / Rheumacin / Rimacid / Slo-Indo) is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID).

Indometacin is used to relieve pain and inflammation in a wide range of musculoskeletal conditions, including various forms of arthritis, gout, muscle sprains and strains, back pain, tendinitis and pain following orthopaedic procedures. It can also be used to relieve period pain.

Indometacin works by blocking the action of a substance in the body called cyclo-oxygenase (COX). Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced by the body in response to injury and certain diseases and conditions, and cause pain, swelling and inflammation. Indometacin blocks the production of these prostaglandins and is therefore effective at reducing inflammation and pain.

 
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Inderal

Inderal (Propranolol) is used for treating high blood pressure and angina pectoris (chest pain).

Drug Name

Inderal (Propranolol)

Drug Uses

Inderal is for treating high blood pressure;
prevention of angina pectoris (chest pain);
management of a heart condition called hypertrophic subaortic stenosis;
treating and preventing certain abnormal or rapid heart rhythms;
improvement of survival after a heart attack in certain patients;
treatment of tremor; prevention of migraine headaches;
and treating symptoms of adrenal gland tumors.

How to use

Use Inderal as directed by your doctor.
Take Inderal by mouth with or without food, but it should be taken at the same time daily and consistently either on an empty stomach or with food;
Do not take antacids containing aluminum within 2 hours of taking Inderal;
Continue to use Inderal even if you feel well. Do not miss any doses.
Ask your health care provider any questions you may have about how to use Inderal.

Drug Class and Mechanism

Inderal is a beta-adrenergic blocking agent. It works by slowing down the heart and reducing blood pressure, which helps it pump more efficiently and reduces the workload on the heart.

Missed Dose

If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. If more than one dose is missed, contact your doctor or pharmacist.

Storage

Store Inderal between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Inderal out of the reach of children and away from pets. 
 
 
 

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Imitrex (Sumatriptan / Imigran)




Imitrex is a drug in tablet form that has sumatriptan as the active element. Imitrex also contains inactive elements such as the following:

  • Croscarmellose sodium
  • Dibasic calcium phosphate
  • Magnesium stearate
  • Microcrystalline cellulose
  • Sodium bicarbonate
  • Hypromellose
  • iron oxide
  • titanium dioxide
  • traction
Imitrex is a drug used to alleviate the headache brought about by migraine attacks.

Imitrex Indications

Imitrex is primarily used in treating a migraine attack. Imitrex is not intended for use in preventing migraine attacks but rather it is intended to relieve the migraine. Imitrex may also be used for purposes other than those indicated in this guide.

Imitrex Warnings

Imitrex should not be administered to patients who have had a previous symptoms, history or signs of the following:

  • alchemic cardiac syndrome, whose symptoms include
    • angina pectoris of any type
    • all forms of myocardial infarction
    • silent myocardial ischemia
  • cerebrovasular syndrome, whose symptoms include
    • strokes of any type as well as transient ischemic attacks
  • peripheral vascular syndrome, whose symptoms include
    • ischemic bowel disease
Imitrex should also not be administered to patients who have the following conditions;

      • uncontrolled hypertension
      • hemiplegic or basilar migraine
      • allergy or hypersensitivity to sumatriptan or any of the other inactive elements mentioned in the drug information
      • severe hepatic impairment
Caution should also be employed when taking Imitrex during pregnancy or when breastfeeding a baby.

Imitrex Intake Guidelines

Imitrex should be taken in exactly as described by your doctor. If there are matters that you do not understand, refer to your doctor, nurse or a pharmacist and ask him or her to explain those matters to you.
Make sure to follow all of your doctor’s instructions when taking in Imitrex.

Imitrex Dosage

Dosage of Imitrex should be obtained from your doctor. Dosage may vary from person to person with regards to a variety of factors, which include severity of the condition, age and others.
Do not take in more or less of Imitrex so as not to alter its affects and to prevent overdose.

Imitrex Overdose

If you think you might be experiencing overdose of Imitrex, seek immediate medical attention or call poison control. Inform your doctor afterwards.
Overdose symptoms of Imitrex in ANIMALS include the following:

  • convulsions
  • tremor
  • paralysis
  • inactivity
  • ptosis
  • erythema of the extremities
  • abnormal respiration
  • cyanosis
  • ataxia
  • mydriasis
  • salivation
  • lacrimation
Symptoms of overdose in humans may be a whole lot different from the overdose symptoms of animals.

Imitrex Missed Dose

Imitrex doses are used only during migraine attacks. A missed dose of Imitrex is therefore not an issue.

Imitrex Side Effects

Imitrex may have any of the following serious side effects:

  • Paresthesia
  • Warm or cold sensations
  • pressure sensations
  • pain or tightness in the Chest area
  • pain, tightness or pressure in the neck, throat or jaw area
  • Malaise or fatigue
  • Vertigo
If you experience any of these, continue using Imitrex but inform your doctor immediately.
Other side effects may also occur when you take Imitrex. Inform your doctor if you experience anything unusual while or after taking Imitrex.

Imitrex Drug Reactions

Imitrex has been known to interact with Monoamine Oxidase Inhibitors and alcohol. Other drugs may also interact with Imitrex. Inform your doctor if you are taking any medications other than Imitrex including over the counter prescriptions such as vitamins, minerals and even herbal products.

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